Griffin
Skype could be considered the best—and worst—thing to ever happen to podcasting. The ability to interview guests remotely is, of course, invaluable. Horrendous audio due to digital artifacts and bad microphones? Not so much. While the pros and cons of Skype recording are stark in contrast, it is certainly possible to maximize the benefits, while minimizing the drawbacks.
While probably the most common, Skype is just one of many voice over IP (VoIP) systems that you can use to interview podcast guests remotely. So, most of the tips here